Team:TU-Munich/Project/Bioaccumulation

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BioAccumulation

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BioAccumulation is a possibility to remove xenobiotics from the environment by binding them to a protein that has been designed for this purpose.





The Fluorescein binding Anticalin FluA

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There are a broad range of natural as well as engineered binding proteins availible. The most commonly known binding proteins are antibodies which defend mammals against pathogens and toxins. Beside these natural binding proteins there are more and more designed binding proteins such as (1) Anticalins based on a lipocalin scaffold (Ref), (2) Affibodies derived from the z-domain of the antibody-binding protein A (Ref) and (3) DARPins that are based on an ankyrin scaffold.


Glutathione S-transferase

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Protein Phosphotase 1 - A molecular mop for Microcystin

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