Quantitative App

DNA binding to TALEs

The positive DNA's are colored red, negative DNA is green, TALEs are black and after binding (i.e. saturation) they turn blue. The sliders under "global settings"€ are parameters needed before the simulation runs. Given that a simulation can take 30 seconds to complete, they should not be changed frequently as it will take longer to show the results. The sliders under "€œdisplay settings"€ are parameters needed after the simulation runs. Their responses are much faster and are best played by clicking on the plus sign to the right and hit "€œPlay". If you only see a grey box, you may need to install the Mathematica CDF Player. The download link can be found here. Otherwise, the data from our model, as well as images of the app we designed, can be found on the quantitative modelling page.

Enzyme kinetics of horseradish peroxidase

Enzyme kinetics of beta-galactosidase

Frequently Asked Questions

1. Can I see your code?

Sure! Here it is, written in Mathematica 9.0.0.

2. I see a block of text with red background instead of the squares. What should I do?

Don't worry, everything is under control. If you have just changed the display setting, please reset your current time to 1. If you changed any of the global setting, just wait for at least 30 seconds for the app to calculate the new model.