Overview

This module mainly consist of specific proteins secreted by enginereed bacteria which act as a tumor killer. Our proteins are e4of4 and apoptin. Following bacterial secretion, spesific proteins penetrate into cancer cells and induce apoptosis within the cells.Also, recent studies have reported  that; apoptin and e4of4 proteins are  succesful at achieving apoptosis and are only cancer spesific. At this point, tumor specificity  is very important because there are risks of damaging healthy cells at contemporary cancer treatment.   In our project, we used mpg and tat peptides for penetrating cancer cells together with spesific proteins and we aimed to decrease growth rate of  cancer populations.