Team:ETH Zurich/Modeling

From 2013.igem.org

(Difference between revisions)
Line 24: Line 24:
=''Mine Cells''=
=''Mine Cells''=
-
<p>The Mine Cells produce the signalling molecule, by constitutive expression of ''luxI'' gene.
+
<p>The Mine Cells lead to the synthesis the signalling molecule, by constitutive expression of ''luxI'' gene. To reveal the nature of the cells, a coloured-substrate reaction is triggered upon addition of ''5-Bromo-4-chloro-3-indoxyl-N-acetyl-beta-D-glucosaminide''; given that the glycoside hydrolase ''NagZ'' is expressed constitutively. <br><br> The ODEs for the states involved in the sender module are given below:
</p>  
</p>  
 +
<math>$dLuxI/dt $</math>
= ''Biosensors'' =
= ''Biosensors'' =
hg
hg

Revision as of 14:26, 17 August 2013

Header2.png
80px-Eth igem logo.png


The change of the species concentrations in time is given by non-linear ordinary differential equations (ODEs), most of which follow Hill kinetics. The parameters we used in the model are derived from literature.

Mine Cells

The Mine Cells lead to the synthesis the signalling molecule, by constitutive expression of luxI gene. To reveal the nature of the cells, a coloured-substrate reaction is triggered upon addition of 5-Bromo-4-chloro-3-indoxyl-N-acetyl-beta-D-glucosaminide; given that the glycoside hydrolase NagZ is expressed constitutively.

The ODEs for the states involved in the sender module are given below:

<math>$dLuxI/dt $</math>

Biosensors

hg