Detector

Transcription Activator-Like Effectors (TALEs) are naturally occurring proteins that bind to DNA. These proteins are found in Xanthomonas species, a plant pathogen, and originally serve as a pathogenic factor. Because TALEs have a highly conserved modular region for DNA binding, they are particularly amenable to genetic engineering and customization. To find out more about what are TALEs, how they work and how they have been used for, check our Background page.

We have engineered a TALE that binds to the shiga toxin II gene, Stx2 in E. coli and other entero-haemorrhagic bacteria.

To learn more about the design consideration of the TALEs click here .

For characterization data on E. coli click here .