Team:ETH Zurich/Modeling/Analytical Approximations

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Steady State AHL Gradient Approximation

In the reaction-diffusion model we have formalized the gradient establishment and we solved the resulting partial differential equation numerically. Now, the aim is to derive a suitable analytical approximation.

Kolmogorov-Petrovsky-Piskounov Equation

A reaction–diffusion equation concerning the concentration of a single molecule in one spatial dimension is known as the Kolmogorov-Petrovsky-Piskounov Equation. In our case, the equation for AHL has the following general structure:

\begin{align} \frac{\partial AHL(\textbf{r},t)}{\partial t} = Diff(AHL(\textbf{r},t),\textbf{r}) + R(AHL(\textbf{r},t)) \end{align}

And a less general form, as derived for the reaction-diffusion model for AHL:

\begin{align} \frac{\partial AHL(\textbf{r},t)}{\partial t} = C_{agar} \cdot D_{AHL} \nabla^{2} AHL(\textbf{r},t) + DF \cdot (\alpha_{AHL} \cdot [LuxI](\textbf{r},t)-d_{AHL,i} \cdot [AHL](\textbf{r},t))_{MineCell} + DF \cdot (-d_{AHL,i} \cdot [AHL](\textbf{r},t))_{ReceiverCell}- d_{AHL,e} \cdot [AHL](\textbf{r},t)