Team:Marburg
From 2013.igem.org
m |
m |
||
Line 7: | Line 7: | ||
Recently, the sunlight-driven microalgae ''Phaeodactylum tricornutum'' has been established as an elegant tool for the production of proteins (Phaectory). A major - however yet unchallenged - advantage of this system is the production of advanced proteins with specific posttranslational modifications. A further major advantage is the ability of their direct secretion into the medium, which allows easy purification with low effort and costs. Our mission is to challenge Phaectory as a system for the convenient production of antibodies. We want to take advantage of the excellent secretion and ability of posttranslational modification and make the system accessible to following iGEM teams. | Recently, the sunlight-driven microalgae ''Phaeodactylum tricornutum'' has been established as an elegant tool for the production of proteins (Phaectory). A major - however yet unchallenged - advantage of this system is the production of advanced proteins with specific posttranslational modifications. A further major advantage is the ability of their direct secretion into the medium, which allows easy purification with low effort and costs. Our mission is to challenge Phaectory as a system for the convenient production of antibodies. We want to take advantage of the excellent secretion and ability of posttranslational modification and make the system accessible to following iGEM teams. | ||
- | [[File: | + | [[File:Mr-without-1000px-Fabrik horizontal.png|1000px|center]] |
<html><div class="home"> | <html><div class="home"> | ||
<div class="home_youtube"> | <div class="home_youtube"> |
Revision as of 11:09, 22 September 2013
Antibodies produced by sunlight
The use of proteins in medical treatment and diagnosis is steadily increasing. Many pharmaceutically relevant proteins, such as antibodies, have a complex biological structure with specific posttranslational modifications. Furthermore, these proteins need to be highly pure because of their use in diagnostics and treatment. Therefore, a major challenge is the development of systems that produce highly pure, posttranslational modified pharmaceutical proteins - best at low costs.
Recently, the sunlight-driven microalgae Phaeodactylum tricornutum has been established as an elegant tool for the production of proteins (Phaectory). A major - however yet unchallenged - advantage of this system is the production of advanced proteins with specific posttranslational modifications. A further major advantage is the ability of their direct secretion into the medium, which allows easy purification with low effort and costs. Our mission is to challenge Phaectory as a system for the convenient production of antibodies. We want to take advantage of the excellent secretion and ability of posttranslational modification and make the system accessible to following iGEM teams.