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<p>When we start our iGEM project, we spent a few weeks to read papers in synthetic biology and review previous projects. We realized that there is no website or database that has systematically record all existing synthetic biology projects. Inspired by the Registry of Standard Biological Part database, we came up with an ambitious plan that we should make the Registry of Standard Genetic Circuit. Our goal is to collect all previous iGEM projects and all published synthetic biology projects. The documentation of genetic circuits follows the general principle of biobrick foundation: Standardization, all description of genetic circuits should adopt the same format.</p>
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<p>Our database is not static. Users are able to submit their genetic circuit design to our database. Users can also add their comments and experiences to circuits.</p>
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<p>Our database is not only a collection of published circuits but also provide a user friendly platform to redesign and improve the circuits. We provide LGD, a logical genetic designer. LGD is also a computer aided graphical designer integrated into our database. User can modify the circuits in the database for their purpose.</p>
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<p>The ultimate goal of our project is to promote sharing in synthetic biology community! We have a future plan of establishing a community based on Mind Road and LGD, for we clearly know the importance of <em>sharing</em> design. To make the sharing efficient and effective, we proposed a technique standard for documentation of a genetic circuit.</p>
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            <p class="lead">Have a glimpse of our project.</p>
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        <h2 class="ui dividing header">Motivation</h2>
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        <p>Our project focuses on genetic circuits. In the last ten years, iGEM competition has produced and collected thousands of biobricks. And extensive efforts have been made to create the technique standard for biobricks. A genetic circuit usually composes of several biobricks and can perform some predefined function. Our project aim to go one step further, that we develop the technique standard for genetic circuits and build up a central database for collecting and sharing genetic circuits.</p>
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        <p>So, here are our actions</p>
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        <h3><img src="https://static.igem.org/mediawiki/2013/4/40/Standard%2832%29.png" />Technical standard</h3>
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        <p>We proposed two technical standards this year (RFC 101 and RFC 97) to define logical gene module and genetic circuits.</p>
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        <h3><img src="https://static.igem.org/mediawiki/2013/a/a3/Logo%2832%29.png">Circuit+</h3>
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        <h5>a central database for genetic circuits</h5>
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        <p>Inspired by the Registry of Standard Biological Part database, we came up with an ambitious plan that we should make the Registry of Standard Genetic Circuit. Our goal is to collect all previous iGEM projects and all published synthetic biology projects.</p>
 +
        <p>The ultimate goal of our project is to promote sharing in synthetic biology community! We have a future plan of establishing a community based on Mind Road and LGD, for we clearly know the importance of sharing design. To make the sharing efficient and effective, we proposed a technique standard for documentation of a genetic circuit</p>
 +
        <h3><img src="https://static.igem.org/mediawiki/2013/6/60/Lab%2832%29.png" />LGD</h3>
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        <p>LGD is short for Logical Genetic Digram. It is a computer aided graphical generator integrated into our database. User can see the circuits and the relations between parts.</p>
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        <h3><img src="https://static.igem.org/mediawiki/2013/7/71/Humanpractise%2832%29.png" />SBOL</h3>
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        <p>Our software support SBOL. SBOL is used in the data-exchanging interface of the software and users can upload and comment circuits.</p>
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        <h3><img src="https://static.igem.org/mediawiki/2013/2/2d/Clotho%2832%29.png" />Clotho application: Circuit List and TTEC</h3>
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        <p>We developed a Clotho version of circuitplus, with the name “Circuit List”. We also developed TTEC in clotho, which is originally created by SUSTC-Shenzhen-B in 2012.</p>
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Latest revision as of 03:26, 29 October 2013

SUSTC-ShenZhen-B

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Overview

Have a glimpse of our project.

Motivation
Actions
Technical standard Circuit+ LGD SBOL Clotho application: Circuit List and TTEC
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Motivation

Our project focuses on genetic circuits. In the last ten years, iGEM competition has produced and collected thousands of biobricks. And extensive efforts have been made to create the technique standard for biobricks. A genetic circuit usually composes of several biobricks and can perform some predefined function. Our project aim to go one step further, that we develop the technique standard for genetic circuits and build up a central database for collecting and sharing genetic circuits.

Actions

So, here are our actions

Technical standard

We proposed two technical standards this year (RFC 101 and RFC 97) to define logical gene module and genetic circuits.

Circuit+

a central database for genetic circuits

Inspired by the Registry of Standard Biological Part database, we came up with an ambitious plan that we should make the Registry of Standard Genetic Circuit. Our goal is to collect all previous iGEM projects and all published synthetic biology projects.

The ultimate goal of our project is to promote sharing in synthetic biology community! We have a future plan of establishing a community based on Mind Road and LGD, for we clearly know the importance of sharing design. To make the sharing efficient and effective, we proposed a technique standard for documentation of a genetic circuit

LGD

LGD is short for Logical Genetic Digram. It is a computer aided graphical generator integrated into our database. User can see the circuits and the relations between parts.

SBOL

Our software support SBOL. SBOL is used in the data-exchanging interface of the software and users can upload and comment circuits.

Clotho application: Circuit List and TTEC

We developed a Clotho version of circuitplus, with the name “Circuit List”. We also developed TTEC in clotho, which is originally created by SUSTC-Shenzhen-B in 2012.

© SUSTC-ShenZhen-B

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