Team:Heidelberg/Project/Achievements

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                         <h1 style="float:left"><span style="font-size:150%;color:#333333;">Achievements.</span><span class="text-muted" style="font-size:90%"> Medal Requirements for Wet-Lab Teams.</span></h1>
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                         <h1 style="float:left"><span style="font-size:150%;color:#333333;">Achievements.</span><span class="text-muted" style="font-size:85%"> Introducing NRPS to Synthetic Biology.</span></h1>
<img src="https://static.igem.org/mediawiki/2013/7/74/Goldmedal.JPG.png" style="float:left; max-height:100px; margin-left:7%;">
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<center><img style="width:100%; margin-top:5%; margin-bottom:2%" src="https://static.igem.org/mediawiki/2013/d/d3/Heidelberg_achievements_Top.png" ></img></center>
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<a class="fancybox fancyGraphical" href="https://static.igem.org/mediawiki/2013/3/3e/Heidelberg_Achievements_sidebar.png">
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    <img style="width:100%; margin-top:2%; padding:1%;border-style:solid;border-width:0px;border-radius: 5px;" src="https://static.igem.org/mediawiki/2013/3/3e/Heidelberg_Achievements_sidebar.png" ></img>
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                                <div class="col-md-10 jumbotron" style="background-image:url(https://static.igem.org/mediawiki/2013/6/68/Heidelberg_Achievements_Haken2.png); background-size:100%; font-size:14px">
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Automated Design of <b>Custom Non-Ribosomal Peptide Synthetases</b>
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<br><br><br>
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Production of <b><a href="https://2013.igem.org/Team:Heidelberg/Project/Tyrocidine">Synthetic Peptides</a></b> in different engineered <em>E. coli</em> Hosts
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<br><br><br>
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Invention of a <a href="https://2013.igem.org/Team:Heidelberg/Project/Indigoidine-Tag">Universal Tag</a></b> for Non-Ribosomal Peptide labeling <em>in vivo</em>
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<br>
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Using the <a href="https://2013.igem.org/Team:Heidelberg/Project/Indigoidine-Tag">Tag</a> for <b>peptide characterization and quantification of production</b>
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<br><br><br>
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Application of <a href="https://2013.igem.org/Team:Heidelberg/Project/Delftibactin">delftibactin NRP</a> for <b>sustainable Gold Recycling</b>
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<br><br><br>
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Introducing our standardized Framework for Production of Synthetic Peptides to the Synbio Community: <b><a href="https://2013.igem.org/Team:Heidelberg/RFCs">RFC 99 and RFC 100</a></b>
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<br>
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<b>Having lots of <a href="<a href="https://2013.igem.org/Team:Heidelberg/Team/Gallery">fun</a> and very much looking forward to the Jamboree in Boston</b>
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<br><br>
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                        <h1 style="float:left"><span style="font-size:150%;color:#333333;">Medal Requirements.</span><span class="text-muted" style="font-size:85%"> Aiming for Gold.</span></h1>
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<img src="https://static.igem.org/mediawiki/2013/7/74/Goldmedal.JPG.png" style="float:left; max-height:100px; margin-left:7%;">
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                     <span class="requirement">We submitted RFC99 and RFC100!</span>
                     <span class="requirement">We submitted RFC99 and RFC100!</span>
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                     <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;;" data-title="New standard - RFC" data-placement="right" data-content='Two different RFCs were submitted as new standard. You can have a look yourself:&lt;a href="/Team:Heidelberg/RFCs"  target="_blank"&gt;&lt;b&gt;RFC99&lt;/b&gt;&lt;/a&gt; and &lt;a href="/Team:Heidelberg/RFCs" &gt;&lt;b&gt;RFC100&lt;/b&gt;&lt;/a&gt;!'></span>
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                     <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;;" data-title="New standard - RFC" data-placement="right" data-content='We developed a standardized framework for the production of synthetic peptides based on engineered NRPSs. Our framework is documented in &lt;a href="/Team:Heidelberg/RFCs#rfc99"  target="_blank"&gt;&lt;b&gt;RFC 99&lt;/b&gt;&lt;/a&gt; and &lt;a href="/Team:Heidelberg/RFCs" &gt;&lt;b&gt;RFC 100&lt;/b&gt;&lt;/a&gt;!'></span>
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                 <a href="/Team:Heidelberg/RFCs#rfc99"><span class="highlight_button" style="background-image: url('https://static.igem.org/mediawiki/2013/0/01/Heidelberg_bn_round_rfc99.png');"></span></a>
                 <a href="/Team:Heidelberg/RFCs#rfc99"><span class="highlight_button" style="background-image: url('https://static.igem.org/mediawiki/2013/0/01/Heidelberg_bn_round_rfc99.png');"></span></a>
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                     <span class="requirement">Have a look on our different parts!</span>
                     <span class="requirement">Have a look on our different parts!</span>
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                     <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click' data-placement="bottom"  data-title="Non-ribosomal peptide synthetase" data-content='&lt;a href="https://2013.igem.org/Team:Heidelberg/Parts"&gt;&lt;b&gt;Here you get to our parts!&lt;/b&gt;&lt;/a&gt;'></span>
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                     <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click' data-placement="bottom"  data-title="Bringing Non-Ribosomal Peptide Synthesis to iGEM- our Parts" data-content='&lt;a href="https://2013.igem.org/Team:Heidelberg/Parts"&gt;&lt;b&gt;Visit our parts page!&lt;/b&gt;&lt;/a&gt;'></span>
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                     <span class="requirement">Thank you for the great help!</span>
                     <span class="requirement">Thank you for the great help!</span>
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                     <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click' data-placement="left"  data-title="Attributions, Sponsors and Acknowledgements"  data-content='We thank our &lt;a href="https://2013.igem.org/Team:Heidelberg/Sponsors"&gt;&lt;b&gt; sponsors&lt;/b&gt;&lt;/a&gt;, &lt;a href="https://2013.igem.org/Team:Heidelberg/Team/Acknoledgements"&gt;&lt;b&gt;people&lt;/b&gt;&lt;/a&gt; donating laboratory equipment and the work of our team.&lt;a href="https://2013.igem.org/Team:Heidelberg/AttributionsII"&gt;&lt;b&gt;(Attribution)&lt;/b&gt;&lt;/a&gt;'></span>
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                     <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-trigger='click' data-placement="left"  data-title="Attributions, Sponsors and Acknowledgements"  data-content='We thank our &lt;a href="https://2013.igem.org/Team:Heidelberg/Sponsors"&gt;&lt;b&gt; sponsors&lt;/b&gt;&lt;/a&gt;, &lt;a href="https://2013.igem.org/Team:Heidelberg/Team/Acknoledgements"&gt;&lt;b&gt;all people&lt;/b&gt;&lt;/a&gt; that kindly shared their laboratory equipment and constructs with us and &lt;a href="https://2013.igem.org/Team:Heidelberg/AttributionsII"&gt;&lt;b&gt;attribute&lt;/b&gt;&lt;/a&gt; the work of our team!'></span>
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                     <span class="check"></span>
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                     <span class="requirement">Poster is prepared for the European Jamboree in Lyon!</span>
                     <span class="requirement">Poster is prepared for the European Jamboree in Lyon!</span>
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                     <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Poster presentation at European jamboree" data-content='We are looking forward to see you at the poster presentation!'></span>
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                     <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="Poster presentation at European jamboree" data-content='Yupi! We won the prize for the best poster!!!'></span>
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                     <span class="requirement">New BioBricks are submitted!</span>
                     <span class="requirement">New BioBricks are submitted!</span>
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                     <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-placement="bottom"  data-title="New submitted Biobricks" data-content='We submitted &lt;a href="https://2013.igem.org/Team:Heidelberg/Parts"&gt;&lt;b&gt;20 parts&lt;/b&gt;&lt;/a&gt; to the parts registry - ranging from the basis for a NRPS-module library, to novel NRPSs and constructs, where entirely synthetic protein-domains were introduced.'></span>
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                     <span class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-placement="bottom"  data-title="New submitted Biobricks" data-content='We submitted &lt;a href="https://2013.igem.org/Team:Heidelberg/Parts"&gt;&lt;b&gt;20 well characterized parts&lt;/b&gt;&lt;/a&gt; to the parts registry - ranging from the basic NRPS-modules and custom NRPSs producing peptides of choice to constructs for NRP tagging and NRPS constructs, where entirely synthetic NRPS-domains were introduced.'></span>
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                     <span class="requirement">Novel approach to ownership and sharing is described!</span>
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                     <span class="requirement">Novel approach to ownership and sharing as well as safety is described!</span>
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                     <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="NRPS-Designer" data-placement="left"  data-content='Feel free to visit our &lt;a href="https://2013.igem.org/Team:Heidelberg/Safety"&gt;&lt;b&gt;Safety&lt;/b&gt;&lt;/a&gt;'></span>
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                     <span  class="btn btn-default btn-lg medal-requirement glyphicon glyphicon-hand-right" style="font-size: 11px;" data-title="NRPS-Designer" data-placement="left"  data-content="The &lt;a href='http://igem2013.bioquant.uni-heidelberg.de/NRPSDesigner/'&gt;&lt;b&gt;NRPSDesigner&lt;/b&gt;&lt;/a&gt; software is our way of sharing our knowledge about NRPS engineering with the iGEM community. During the development and programming of the NRPSDesigner we employed different &lt;a href='https://2013.igem.org/Team:Heidelberg/OpenSource'&gt;&lt;b&gt;open source&lt;/b&gt;&lt;/a&gt; software packages and also improved some of those in order to support the open source programming community. Please feel free to visit our &lt;a href='https://2013.igem.org/Team:Heidelberg/Safety'&gt;&lt;b&gt;Safety page&lt;/b&gt;&lt;/a&gt; also."></span>
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Latest revision as of 03:52, 29 October 2013

Achievements. Introducing NRPS to Synthetic Biology.


Automated Design of Custom Non-Ribosomal Peptide Synthetases


Production of Synthetic Peptides in different engineered E. coli Hosts


Invention of a Universal Tag for Non-Ribosomal Peptide labeling in vivo
Using the Tag for peptide characterization and quantification of production


Application of delftibactin NRP for sustainable Gold Recycling


Introducing our standardized Framework for Production of Synthetic Peptides to the Synbio Community: RFC 99 and RFC 100
Having lots of fun and very much looking forward to the Jamboree in Boston

Medal Requirements. Aiming for Gold.



Best New Standard
We submitted RFC99 and RFC100!
Parts!
Have a look on our different parts!
Attribution and Contribution!
Thank you for the great help!
Bronze Medal Requirements
Team is registered!
Judging form is completed and submitted!
Project description of the Philosopher's Stone online!
Poster is prepared for the European Jamboree in Lyon!
New standard BioBrick is documented!
Silver Medal Requirements
New BioBricks are characterized!
New BioBricks are submitted!
Implications for ethics are pointed out!
Gold Medal Requirements
Functions of existing BioBrick was improved!
We helped other iGEM teams!
Novel approach to ownership and sharing as well as safety is described!
Thanks to