Team:Heidelberg

From 2013.igem.org

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{{:Team:Heidelberg/Templates/StartPage|Welcome to out team page|}}
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{{:Team:Heidelberg/Templates/bootstrap-css}}
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{{:Team:Heidelberg/Templates/basic-css}}
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{{:Team:Heidelberg/Templates/style-css}}
<html>
<html>
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<style>
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<style type="text/css">
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#navigation-bar * {
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color:transparent;
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ul {
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    line-height: 1em;
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}
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.item ul {
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    left: 50%;
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}
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/* Image map styles */
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.imageMap {width:100%; position:relative;}
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.imageMap img {display:block; width:100%; border-radius:20px;}
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.imageMap .hotspots {width:100%; height:100%; position:absolute; left:0; top:0; visibility:hidden;}
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.imageMap a {display:block; position:absolute; z-index:100; opacity:0.2; filter: alpha(opacity=20); border:1px solid transparent; border-radius:10px;}
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.imageMap a.p1 {height: 28%;left: 14.3%;top: 37%;transform: rotate(40deg);-ms-transform:rotate(40deg); /* IE 9 */
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-webkit-transform:rotate(40deg); /* Safari and Chrome */ width: 4.3%;}
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.imageMap a.p2 {height: 28%;left: 19.1%;top: 38.5%;transform: rotate(-18deg);-ms-transform:rotate(-18deg); /* IE 9 */
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-webkit-transform:rotate(18deg); /* Safari and Chrome */width: 6.3%;}
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.imageMap a.p6 {height: 38%;left: 42%;top: 27%;transform: rotate(23deg);-ms-transform:rotate(23deg); /* IE 9 */
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-webkit-transform:rotate(23deg); /* Safari and Chrome */width: 5.6%;}
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.imageMap a.p7 {height: 46%;left: 48.8%;top: 20%;transform: rotate(-27deg);-ms-transform:rotate(-27deg); /* IE 9 */
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-webkit-transform:rotate(-27deg); /* Safari and Chrome */width: 6.3%;}
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-webkit-transform:rotate(-45deg); /* Safari and Chrome */width: 4%;}
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.imageMap a.p10 {height: 28.5%;left: 68.8%;top: 38%;transform: rotate(22deg);-ms-transform:rotate(22deg); /* IE 9 */
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-webkit-transform:rotate(22deg); /* Safari and Chrome */width: 4.1%;}
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.imageMap a.p11 {height: 46%;left: 73%;top: 20%;transform: rotate(-18deg);-ms-transform:rotate(-18deg); /* IE 9 */
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-webkit-transform:rotate(-18deg); /* Safari and Chrome */width: 6.3%;}
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.imageMap a.p12{height: 41%;left: 81.7%;top: 25%;transform: rotate(24.5deg);-ms-transform:rotate(24.5deg); /* IE 9 */
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-webkit-transform:rotate(24.5deg); /* Safari and Chrome */width: 5.6%;}
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.imageMap a.p13{height: 29%;left: 87.8%;top: 36.5%;transform: rotate(40deg);-ms-transform:rotate(40deg); /* IE 9 */
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-webkit-transform:rotate(40deg); /* Safari and Chrome */width: 4%;}
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.imageMap a.p14{height: 29%;left: 92.4%;top: 38%;transform: rotate(-16deg);-ms-transform:rotate(-16deg); /* IE 9 */
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-webkit-transform:rotate(-16deg); /* Safari and Chrome */width: 4%;}
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                .imageMap a.p15 {height: 28%;left: 21.3%;top: 11.7%;transform: rotate(26deg);;-ms-transform:rotate(26deg); /* IE 9 */
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-webkit-transform:rotate(26deg); /* Safari and Chrome */width: 4.3%;}
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                .imageMap a.p16 {height: 28%;left: 66.5%;top: 10.5%;transform: rotate(-10deg);;-ms-transform:rotate(-10deg); /* IE 9 */
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-webkit-transform:rotate(-10deg); /* Safari and Chrome */width: 4.3%;}
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.imageMap:hover .hotspots {visibility:visible;}
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.imageMap p strong {display:block; padding:0; margin:0; font: bold 25px/30px 'times new roman',serif; color:#000;}
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.imageMap p {padding:0; margin:0; font: normal 18px/22px 'times new roman',serif; color:#444;}
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.imageMap b {display:block; position:absolute; background:url(trans.gif); z-index:200; opacity:0.2; filter: alpha(opacity=20); padding:1px;
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-webkit-transition:0.75s;
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-moz-transition:0.75s;
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-o-transition:0.75s;
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transition:0.75s;
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}
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.imageMap b.b1 {left:11%; top:5%; width:25%; height:34%;}
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.imageMap b.b2 {left:76%; top:13%; width:21%; height:30%;}
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.imageMap b.b3 {left:5%; top:44%; width:22%; height:42%;}
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.imageMap b.b5 {left:55%; top:64%; width:15%; height:26%;}
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.imageMap b.b6 {left:72%; top:53%; width:25%; height:35%;}
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.imageMap .hotspots div:hover b {width:0; padding:0;}
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.imageMap .hotspots div:hover p {display:block;}
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.imageMap .hotspots div:hover a {background:#fff; z-index:100; opacity:0.3; filter: alpha(opacity=30);}
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/* adapt bootstrap modal so it makes the welcome text a bit more prominent*/
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.modal-backdrop.in {
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    opacity: 0.7;
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}
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.modal-dialog {
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    width:90%;
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}
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.modal-header {
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  border-bottom: medium none;
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}
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.modal-title {
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  font-size:200%;
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  text-align:center;
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}
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.modal-body {
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  padding-top:0px;
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}
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.modal-body * {
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  font-size:1.1em;
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  text-align:justify;
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}
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.btn-group-lg {
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  padding: 0 1.4em;
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}
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.btn-group-lg > .btn {
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  padding-left: 0.85em;
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  padding-right: 0.85em;
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}
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.tour {
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    background-position: left center;
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    background-repeat: no-repeat;
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    background-size: 200px 100px;
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    display: inline-block;
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    height: 100px;
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    width: 100px;
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}
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.tour:hover {
 +
    background-position: right center; 
}
}
</style>
</style>
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<a href="#"><img src="https://static.igem.org/mediawiki/2013/a/a6/Heidelberg_go_up2.png" style="bottom: 15px;padding: 10px;position: fixed;right: 15px;max-width:70px; z-index:10000000000000;"></a>
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<div style="margin-left:1%; margin-right:1%">
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<a href="https://2013.igem.org" style="left:0.5%;"><img src="https://static.igem.org/mediawiki/2013/b/b3/Heidelberg_igem_logo2.png" height="70"></img></a>
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<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert *** -->
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    <div class="row">  
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        <div id="nav" class="navigation col-md-8 col-lg-8">
 +
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            <div class="item team">
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                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/9/9d/Heidelberg_bg_team2.png" style="opacity: 0; width: 52px; height: 52px; top: 0px; left: 0px;" height="199" width="199">
 +
                <a class="icon" href="#"></a>
 +
                <h2 class="">Team</h2>
 +
                <ul style="display: none;">
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                    <li><a href="/Team:Heidelberg/Team">Team Members</a></li>
 +
                    <li><a href="/Team:Heidelberg/AttributionsII">Attributions</a></li>
 +
                    <li><a href="/Team:Heidelberg/Team/Collaboration">Collaborations</a></li>
 +
                    <li><a href="/Team:Heidelberg/Team/Sponsors">Sponsors</a></li>
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<img style="max-width:40px; position:absolute; right: 170px;top:130px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/Team/Gallery">Gallery</a></li>
 +
                </ul>
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            </div>
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            <div class="item project">
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                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/9/9e/Heidelberg_bg_project.png" style="opacity: 0; width: 52px; height: 52px; top: 0px; left: 0px;" height="199" width="199">
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                <a class="icon" href="#"></a>
 +
                <h2 class="">Project</h2>
 +
                <ul style="display: none;">
 +
   
 +
                    <img style="max-width:40px; position:absolute; right: 200px;top:0px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
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<img style="max-width:40px; position:absolute; right: 200px;top:140px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
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<img style="max-width:40px; position:absolute; right: 200px;top:100px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/NRPS">Background</a></li>
 +
                    <li><a href="/Team:Heidelberg/Project">Overview</a></li>
 +
                   
 +
                    <li><a href="/Team:Heidelberg/Project/Tyrocidine">Synthetic Peptides</a></li>
 +
                    <li><a href="/Team:Heidelberg/Project/Indigoidine-Tag">Indigoidine-Tag</a></li>
 +
                    <li><a href="/Team:Heidelberg/Project/Tag-Optimization">Tag Optimization</a></li>
 +
                    <li><a href="/Team:Heidelberg/Project/Delftibactin">Gold Recycling</a></li>
 +
                    <li><a href="/Team:Heidelberg/Project/Achievements">Achievements</a></li>
 +
                   
 +
                </ul>
 +
            </div>
 +
            <div class="item notebook">
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                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/0/07/Heidelberg_bg_notebook.png" style="opacity: 0; width: 52px; height: 52px;" height="199" width="199">
 +
                <a class="icon" href="#"></a>
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 +
                <h2>Notebook</h2>
 +
                <ul style="display: none;">
 +
                    <li><a href="/Team:Heidelberg/Indigoidine">Indigoidine</a></li>
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                    <li><a href="/Team:Heidelberg/Tyrocidine">Module Shuffling</a></li>
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                    <li><a href="/Team:Heidelberg/Delftibactin">Gold Recycling</a></li>
 +
                    <li><a href="/Team:Heidelberg/NRPSDesigner">NRPSDesigner</a></li>               
 +
                    <li><a href="/Team:Heidelberg/Materials">Materials</a></li>
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                    <li><a href="/Team:Heidelberg/Notebook/Methods">Methods</a></li>   
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                </ul>
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            </div>
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            <div class="item parts">
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                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/f/fc/Heidelberg_parts2.png" style="opacity: 0; width: 52px; height: 52px; top: 0px; left: 0px;" height="199" width="199">
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                <a class="icon" href="#"></a>
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                <h2>Parts</h2>
 +
                <ul>
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                    <li><a href="/Team:Heidelberg/Parts">Submitted parts</a></li>
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                    <img style="max-width:40px; position:absolute; right: 170px;top:25px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/Favorite_Parts">Favorite parts</a></li>
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                    <img style="max-width:40px; position:absolute; right: 170px;top:65px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/RFCs">Our RFCs</a></li>
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                </ul>
 +
            </div>
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            <div class="item software">
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                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/9/9d/Heiderlberg_bg_software.png" style="opacity: 0; width: 52px; height: 52px; top: 0px; left: 0px;" height="199" width="199">
 +
                <a class="icon" href="#"></a>
 +
                <h2 class="">Software</h2>
 +
                <ul style="display: none;">
 +
                    <li><a href="/Team:Heidelberg/Project_Software">Project</a></li>
 +
                    <li><a href="http://igem2013.bioquant.uni-heidelberg.de/NRPSDesigner/">NRPSDesigner</a></li>
 +
                    <li><a href="/Team:Heidelberg/HumanPractice/iGEM42">iGEM42</a></li>
 +
<img style="max-width:40px; position:absolute; right: 150px;top:100px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/OpenSource">Open Source</a></li>
 +
                    <img style="max-width:40px; max-height:40px; position: absolute; right: 150px; top: 140px;" src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/Project/AchievementsSoftware">Achievements</a></li>
 +
                </ul>
 +
            </div>
 +
            <div class="item human">
 +
                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/0/09/Heidelberg_bg_human.png" style="opacity: 0; width: 52px; height: 52px; top: 0px; left: 0px;" height="199" width="199">
 +
                <a class="icon" href="#"></a>
 +
                <h2>Human Practice</h2>
 +
                <ul>
 +
                    <li><a href="/Team:Heidelberg/HumanPractice">Overview</a></li>
 +
<img style="max-width:40px; position:absolute; right:190px;top:25px" src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/HumanPractice/BroadPublic">Broad Public</a></li>
 +
<img style="max-width:40px; position:absolute; right:190px;top:65px" src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/HumanPractice/Survey">Survey</a></li>
 +
                    <li><a href="/Team:Heidelberg/HumanPractice/YoungGeneration">Young Generation</a></li>
 +
                    <li><a href="/Team:Heidelberg/HumanPractice/Artists">Arts and Science</a></li>
 +
                    <li><a href="/Team:Heidelberg/HumanPractice/BeyondScience">Beyond Science</a></li>
 +
                    <li><a href="/Team:Heidelberg/HumanPractice/Experts">Experts</a></li>
 +
                </ul>
 +
            </div>
 +
            <div class="item safety">
 +
                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/7/70/Heidelberg_bg_safety.png" style="opacity: 0; width: 52px; height: 52px; top: 0px; left: 0px;" height="199" width="199">
 +
                <a class="icon" href="#"></a>
 +
                <h2>Safety</h2>
 +
                <ul>
 +
                    <li><a href="/Team:Heidelberg/Safety">Safety</a></li>
 +
                </ul>
 +
            </div>
 +
            <div class="item model">
 +
                <img class="circle" alt="" src="https://static.igem.org/mediawiki/2013/archive/1/1d/20131021232127!Heidelberg_model_bg.png" style="opacity: 0; width: 52px; height: 52px; top: 0px; left: 0px;" height="199" width="199">
 +
                <a class="icon" href="#"></a>
 +
                <h2>Modeling</h2>
 +
                <ul>
 +
                    <img style="max-width:40px; position:absolute; right: 170px;top:0px " src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/Modelling/Gold_Recovery">Gold Recycling</a></li>
 +
                    <img style="max-width:40px; position:absolute; right: 170px; top:40px" src="https://static.igem.org/mediawiki/2013/f/f9/Heidelberg-new_button3.png">
 +
                    <li><a href="/Team:Heidelberg/Modelling/Ind_Production">ind-Production</a></li>
 +
                </ul>
 +
            </div>
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<div id="box" style="width: 700px; margin-left: 137px; padding: 5px; border: 3px solid #000; background-color: #fe2b33;">
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<div style="width:90%;margin-top:100px;">
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<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
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<img src="https://static.igem.org/mediawiki/2013/4/43/Heidelberg_start_background2.png" style="z-index:-1;width:100%;">
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This is a template page. READ THESE INSTRUCTIONS.
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<a href="/Team:Heidelberg/RFCs" style="position:absolute;left:24%;top:48%;"  target="_blank"><span class="highlight_button_pulse" style="background-image: url('https://static.igem.org/mediawiki/2013/7/7f/Heidelberg_bn_round_rfc100.png');animation-delay:0.8s;-moz-animation-delay:0.8s;-webkit-animation-delay:0.8s;"></span></a>
 +
<a href="/Team:Heidelberg/RFCs#rfc99" style="position:absolute;left:35%;top:43%;"  target="_blank"><span class="highlight_button_pulse" style="background-image: url('https://static.igem.org/mediawiki/2013/0/01/Heidelberg_bn_round_rfc99.png');animation-delay:0.6s;-moz-animation-delay:0.6;-webkit-animation-delay:0.6s;"></span></a>
 +
<a href="http://igem2013.bioquant.uni-heidelberg.de/NRPSDesigner/" style="position:absolute;left:46%;top:45%;"  target="_blank"><span class="highlight_button_pulse" style="background-image: url('https://static.igem.org/mediawiki/2013/0/0d/Heidelberg_bn_round_NRPSDesigner.png');animation-delay:0.4s;-moz-animation-delay:0.4s;-webkit-animation-delay:0.4s;"></span></a>
 +
<a href="https://2013.igem.org/Team:Heidelberg/Favorite_Parts" style="position:absolute;left:55%;top:55%;"  target="_blank"><span class="highlight_button_pulse" style="background-image: url('https://static.igem.org/mediawiki/2013/7/79/Heidelberg_bn_round_synPart.png');animation-delay:0.2s;-moz-animation-delay:0.2s;-webkit-animation-delay:0.2s;"></span></a>
 +
<a href="https://2013.igem.org/Team:Heidelberg/Favorite_Parts" style="position:absolute;left:61%;top:69%;"  target="_blank"><span
 +
class="highlight_button_pulse" style="background-image: url('https://static.igem.org/mediawiki/2013/0/0b/Heidelberg_bn_round_natPart.png');"></span></a>
</div>
</div>
-
<div id="instructions" style="text-align: center; font-weight: normal; font-size: small; color: #f6f6f6; padding: 5px;">
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        </div>
-
You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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</div>
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<div id="warning" style="text-align: center; font-weight: bold; font-size: small; color: #f6f6f6; padding: 5px;">
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You <strong>MUST</strong> have all of the pages listed in the menu below with the names specified. PLEASE keep all of your pages within your teams namespace. 
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</div>
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</div>
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</html>
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-
<!-- *** End of the alert box *** -->
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<div class="col-md-4 col-lg-4 col-logo" style="margin-top:-3%">
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            <img id='logo' alt="" src="https://static.igem.org/mediawiki/2013/6/60/Heidelberg_team_logo.png" style="margin-right:3%;margin-bottom:5%;width:100%;">
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<p style="font-size:20px; color:#999999; text-align:left"> Grand Prize Winner <br/> Best Foundational Advance Award <br/> Best Poster Europe </p>
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{|align="justify"
 
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'''Welcome on Heidelberg 2013's wiki!'''  <br/> <br/>
 
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We are a highly motivated team of 13 undergraduate students from the University of Heidelberg, all with different scientific backgrounds including Molecular Biotechnology, Biology and Systems Biology. Our team is supervised by Prof. Dr. Roland Eils and Dr. Barbara Di Ventura from the University of Heidelberg and the German Cancer Research Center (DKFZ) and supported by eight advisors.
 
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|[[Image:Heidelberg_logo.png|200px|right|frame]]
 
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'''What we are working on:''' <br/><br/>
 
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Numerous non-ribosomal peptides such as antibiotics, chelators of metals, metabolic and detoxificating enzymes are produced in an alternative ribosome-independent pathway as secondary metabolites, found in fungi and various bacteria. The chain of modules the enzyme - called non-ribosomal peptide synthetase (NRPS) - consists of, subsequently adds a defined amino acid to build a template-independent peptide chain. Every module’s sequence of subdomains furthermore encodes for possible chemical modifications of the amino acid.
 
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<br/><br/>
 
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We will investigate modularity of the NRPS systems giving rise to the assembly of novel, engineered synthetases and subsequent synthesis of artificial non-ribosomal peptides. Currently, we are establishing the introduction of different NRPS pathways into E.coli. Our aim is to prove interchangeability of NRPS modules and domains from different host organisms. Smaller peptide synthetases, e.g. producing dyes, are used for the exchange of domains, whereas more complex synthetases, e.g. producing antibiotics, were chosen to investigate module exchangeability.
 
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<br/><br/>
 
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We wish to share the enormous potential of non-ribosomal peptide synthetases with the iGEM community by establishing a standard system for these synthetases, supported by an implemented software framework. Thereby, we are going to simplify manufacturing and applicability of non-ribosomal peptides in order to offer a cost- and energy-efficient alternative for the synthesis of biomolecules. As secondary metabolites, these peptides play important roles in basic research (such as dyes), pharmaceutical development (such as antibiotics) and recycling (such as chelators).
 
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|align="center"|[[Team:Heidelberg | Team Heidelberg]]
 
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              <span style="font-size:1.5em; color:#999999;"> Grand Prize Winner <br/> Best Foundational Advance <br/> Best Poster Europe <br/> Advance to World Championship</span>
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Latest revision as of 13:46, 24 November 2013

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