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| - | <h1><span style="font-size:170%;color:#FFCC00;">Human Practice.</span><span class="text-muted" style="font-family:Arial, sans-serif; font-size:100%"> Spreading the spirit.</span></h1> | + | <h1><span style="font-size:170%;color:#FFCC00;">Gallery.</span><span class="text-muted" style="font-family:Arial, sans-serif; font-size:100%"> In Remembrance of a Great Time.</span></h1> |
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| - | <p>Besides economical usage of the resource gold, one way to reduce global demands for gold is elevation of gold recovery <span class="citation">[4]</span>. Intriguingly, nature itself offers a structure that has been reported to efficiently extract pure gold from solutions containing gold ions. This fascinating molecule is called Delftibactin and is in fact a small peptide secreted by a metal-tolerant bacterium called <em>Delftia acidovorans</em>.</p>
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| - | <p>This extremophile has the incredible ability to withstand toxic amounts of gold ions in contaminated soil . What is the special feature of Delftibactin enabling precipitation of gold that efficiently? If one could culture these bacteria and produce Delftibactin in large scales, could one potentially recover gold from electronic waste in a cost- and energy-efficient way? But what is the special feature of Delfibactin to precipitate gold that efficiently?</p>
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| - | <a class="fancybox fancyGraphical" href="https://static.igem.org/mediawiki/2013/4/47/Heidelberg_goldrecycling.png" style="float:left; margin-right: 10px;" title="Schematic illustration of the recovery of gold with delftibactin"> | + | <div class="jumbotron"> |
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| - | <img style="width:400px; margin-bottom:10px; padding:1%;border-style:solid;border-width:1px;border-radius: 5px;" src="https://static.igem.org/mediawiki/2013/4/47/Heidelberg_goldrecycling.png" ></img>
| + | Besides the invaluable boost of scientific knowledge, our iGEM project was above all an exciting time. Spending day and night in the lab, celebrating positive results and sharing chocolates after less positive ones tied close friendships. We've spend a great time together worth remembering! |
| - | <figcaption><b>Fig. 1</b> Schematic illustration of the recovery of gold with delftibactin <span class="citation">[6]</span></figcaption> | + | </h2> |
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| - | <p>Delftibactin is no ordinary peptide but a non-ribosomal peptide (NRP) <span class="citation">[5]</span> <span class="citation">[6]</span>. The efficient and non-polutative large-scale production of this NRP in <em>E. coli</em> could revolutionize the recovery of gold from electronic waste and additionally highlight the plethora of versatile applications for non-ribosomal peptide synthetases (NRPSs). The most sriking feature of these non-ribosomal synthetases is their ablity to incorporate far more than the 21 common amino acids into peptides. They make use of numerous modified and even non-proteinogenic amino acids <span class="citation">[7]</span> to assembly peptides of diverse functions.</p>
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| - | <p>Delftibactin is a NRP produced by a hybrid NRPS/ polyketide synthase (PKS) system. In their recent publication, Johnston <em>et al.</em> <span class="citation">[5]</span> predicted that the enzymes responsible for producing delftibactin are encoded on a single gene cluster, hereafter referred to as Del cluster. It comprises 59 kbp encoding for 21 genes. DelE, DelF, DelG and DelH constitute the hybrid NRPS/ PKS system producing delftibactin, with DelE, DelG and DelH being NRPS and DelF the PKS. The remaining enzymes involved in the Delftibactin synthesis pathway are required for NPRS/ PKS maturation or post-synthesis modification of Delftibactin. The predicted activities of the assumed proteins are.
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| - | Besides economical usage of the resource gold, one way to reduce global demands for gold is elevation of gold recovery <span class="citation">[4]</span>. Intriguingly, nature itself offers a structure that has been reported to efficiently extract pure gold from solutions containing gold ions. This fascinating molecule is called Delftibactin and is in fact a small peptide secreted by a metal-tolerant bacterium called <em>Delftia acidovorans</em>.</p>
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| - | <p>This extremophile has the incredible ability to withstand toxic amounts of gold ions in contaminated soil . What is the special feature of Delftibactin enabling precipitation of gold that efficiently? If one could culture these bacteria and produce Delftibactin in large scales, could one potentially recover gold from electronic waste in a cost- and energy-efficient way? But what is the special feature of Delfibactin to precipitate gold that efficiently?</p>
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| - | <p>Besides economical usage of the resource gold, one way to reduce global demands for gold is elevation of gold recovery <span class="citation">[4]</span>. Intriguingly, nature itself offers a structure that has been reported to efficiently extract pure gold from solutions containing gold ions. This fascinating molecule is called Delftibactin and is in fact a small peptide secreted by a metal-tolerant bacterium called <em>Delftia acidovorans</em>.</p>
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| - | <p>This extremophile has the incredible ability to withstand toxic amounts of gold ions in contaminated soil . What is the special feature of Delftibactin enabling precipitation of gold that efficiently? If one could culture these bacteria and produce Delftibactin in large scales, could one potentially recover gold from electronic waste in a cost- and energy-efficient way? But what is the special feature of Delfibactin to precipitate gold that efficiently?</p>
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